Cryptococcal meningitis complicating sarcoidosis
Drs. S.E. Leonhard, Drs. D. Fritz, Prof. dr. D. van de Beek, Dr. M.C. Brouwer
In this article we described a rare complication of sarcoidosis; cryptococcal meningitis. This is an infection of the meninges due to a fungus called 'Cryptococcus neoformans'. This is a extreme rare complication in sarcoidosis patients and can occur when their immune system is weakened due to the disease.
How to monitor safety and efficacy of biologic treatment in rare, therapy-refractory immune-mediated inflammatory diseases?: Making the right clinical decisions for rare diseases with the right tools.
Anne Musters en Sander W. Tas
This article is an editorial in the scientific journal 'Rheumatology'. Evaluating the effects and safety of modern treatment agents which treat rare diseases can be complex, because it can be difficult to properly investigate them in a qualitative clinical trial due to the low number of patients with this disease. Therefore, it is important to adequately describe the effects of these treatments. This article suggests the five domains of the 'Rare IMID Disease Activity Score' (RIDAS).