Sarcoidosis is a complex disease and a lot is still unknown. The diagnosis can be difficult. To diagnosis a patient with 100% certainty the presence of granulomas must be established in affected tissue. However, to acquire biopsy material might sometimes be associated with high mortality or morbidity. Furthermore, not all patient respond well to treatment. Especially in rare manifestations of sarcoidosis this is not well investigated. To improve our undertanding of the disease and to improve the diagnostic process and outcome we conduct scientific research.
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More research projectsRecent publications
Off-labelgebruik van biologicals voor zeldzame immunologische aandoeningen
Anne Musters, Amira Assaf, Dominique L.P. Baeten en Sander W. Tas Patients with serious, immune-mediated inflammatory diseases (IMID's), like sarcoidosis, are increasingly treated with biologicals. Because research in these rare diseases is often very difficult, it is not known in all cases what the effects of the treatment are. In this article we elaborate on the RUBRIC-registry, in which we registrate the efficacy and the safety of these agents.
An electronic nose discriminates exhaled breath of patients with untreated pulmonary sarcoidosis from controls
Dragonieri S, Brinkman P, Mouw E, Zwinderman AH, Carratú P, Resta O, Sterk PJ, Jonkers RE Because making the diagnosis sarcoidosis can be complex, it is important to improve the diagnostic process. In this article we describe an 'electronic nose' to check heter or not it can potentials identify sarcoidosis patients. They did this by comparing the exhaled air of untreated sarcoidosis patients with healthy controls. They did found that the exhaled air was different.
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